ACTIGOLD APIGENIN

Description:

• ACTIGOLD APIGENIN: Clear liquid solution of naturally sourced Apigenin in a carrier of Laurocapram. INCI: Laurocapram, Apigenin. Dosage: 0,1% – 0,5%

Benefits:

• Anti-irritant and anti-inflammatory
• Antioxidant broad-spectrum
• High tolerance and suitable for sensitive skin
• Greater bioavailability and easy absorption
• Helps hair care

Applications:

• Skincare: toners, lotions, aftershave, and sensitive skin lines
• Scalp and haircare: anti-dandruff treatments and anti-hair loss products
• Soothing/anti-redness formulas and urban/sun protection products

Efficacy:

• Modulation of pro-inflammatory mediators
• Antihistamine action
• Antioxidant activity
• Protection against external aggressors
• Increased bioavailability

Graph:

Reduction of IL-1α in three treatments with ACTIGOLD APIGENIN: 

The graph shows the inhibition of IL-1α release in a stimulated cell model after application of apigenin at different concentrations (0,05 μM, 0,5 μM, and 5 μM), compared to the stimulated control and dexamethasone (1 μM). A significant decrease in IL-1α is observed compared to the stimulated control, confirming the potent anti-inflammatory efficacy of apigenin.

(1) Funakoshi-Tago M, Nakamura K, Tago K, Mashino T, Kasahara T., Int Immunopharmacol. 2011 Sep;11(9):1150-9. Epub 2011 Apr 5